I am now a convert to Speedplay pedals, sorry Look but our 24 year relationship is over. The simplicity to get them dialed in is just way too easy from a bike fitter's view.
As a rider I have heard in the past that people did experience "hot spots" under their feet when using Speedplay pedals, but the more I learn from fitting individuals, I can tell that those hot spots are caused not by the pedals but from improper foot/cleat/pedal interface. All of the subject being fitted suring this training required a change in the spindle length to achieve a perfect position on the bike, with 6 needing longer spindles on 1 or both pedals and 1 subject needing to go with shorter spindles.
Back to the fits ... as mentioned before every subject that was fitted presented our group with some challenges however everyone of them left a happy cyclist! The common underlying theme was too long of stems!!! If you are experiencing lower back pain or shoulder pain make sure to revisit your reach! If your hands do not gravitate to the hoods, revisit your reach! There are some great handlebars out there available in shorter reaches and shallower drops which should be considered when building up your new bike or upgrading your old bike.
Until next time ... ride in comfort!